Human Platelets

Abstract

Summary

The rapid incorporation of labeled ¹⁴C from U^-14C-acetate and U^-14C‐ D‐glucose into free glutamic acid, glutamine, aspartic acid, and asparagine shows that human platelets are capable of synthesizing their own amino acids. Differences in the turnover rates of these amino acids indicate that the metabolic pools are localized in compartments. It is also suggested that more than one pool of acetyl CoA and probably at least two separate pools of citric acid cycle intermediates exist.