Abstract
Summary
Leukocyte release was studied in normal rats and in rats subjected to massive leukocyte withdrawal via peritoneal lavage (leukocytapheresis, LAP) using 3HT autoradiography. A significant difference in the emergence time of neutrophils in LAP rats, when compared to normal rats, was observed after flash labeling with 3HT. Peak neutrophil labeling in LAP animals occurred on day 2 following isotope injection, whereas in normal (non‐LAP) animals the peak was seen on days 3‐4. Thus, large numbers of neutrophils entered the peripheral circulation of LAP animals 1‐2 days earlier than normal.
Get full access to this article
View all access options for this article.