Abstract
Summary
Guinea pigs made highly susceptible to intravenous endotoxin with a sublethal dose of CCl4 were not more susceptible to the lethal infection induced by penicillin when the increased susceptibility to endotoxin occurred at the time of the infection induced by penicillin. However, during the recovery phase of CCl4 damage mortality from penicillin was reduced. A mild degree of resistance to the lethal effect of endotoxin did not protect guinea pigs from the lethal effect of penicillin.
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