Abstract
Summary
The response of various transplantable tumors to a fractionated course of radiation therapy has been studied in host mice and rats fed different levels of dietary protein. The parameters employed in evaluating the effect of diet have been: (a) tumor growth, (b) tumor cure, and (c) host survival time. The tumor used in these studies most genetically divergent from its host (Sarcoma 180) showed the most striking response to diet and radiation. Tumors less divergent from their hosts were markedly less responsive. It is proposed that the varying responses obtained in these studies can be explained on the basis of the protein reserves of the host, and the genetic composition of the tumor with respect to its host and the resulting immunological consequences.
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