Abstract
Summary
Spleen cells from Coombs positive 480-500-day-old male NZB mice were incapable of inducing graft-versus-host reactions when injected into (NZBXA) F1 hybrids. This occurred even when the total number of nucleated cells injected was adjusted to contain 15-20 × 106 lymphoid cells. Younger, 45 and 150 day old, NZB mice were capable of inducing graft-versus-host reactions in a normal fashion.
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