Abstract
Summary
Rat TD, splenic, and thymic cells, with or without prior exposure to SRC in vivo, yielded reduced numbers of PFC when the lymphoid cells were incubated for 96 hours in a medium containing PHA-M during 1-4 days of the incubation. The infusion of PHA-P into rats 3 and 2 days before and after the intravenous injection of SRC resulted in a diminution of PFC in the spleen. The administration of PHA-P to rats 1 day before, at the time of, or 1 day after antigen injection resulted in an increase of PFC in the spleen.
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