Abstract
Summary
The influence of growth hormone, plasma glucose, and plasma ketone bodies on cardiac glycogen deposition was studied in fasted intact rats and both non-fasted and fasted alloxan-diabetic rats. The results indicate a close positive correlation between plasma ketones (but not plasma glucose) and cardiac glycogen. Fasting does not increase diabetic myocardial glycogen levels and, unlike normal intact rats, growth hormone did not influence myocardial polysaccharide levels in diabetic rats indicating a possible tissue refractoriness to the hormone or the need for “permissive” amounts of insulin to be present.
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