Abstract
Summary
A cationic (basic) protein, methylated serum albumin, could not be analyzed by immunodiffusion in agar or agarose gels because it would not diffuse through them. Using gels of gelatin solved this problem. This finding may be applicable to gel-diffusion studies of other basic protein antigens, and it indicates that immunodiffusion tests in gelatin can be employed to complement those performed in agar to detect otherwise overlooked cationic antigens and corresponding precipitins.
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