Abstract
Summary
Starvation was found to decrease both the endogenous LM-GPDH level and the induction of LM-GPDH by T3-treat-ment. Different diets of protein, carbohydrate, or fat along with a salt-mixture were used to refeed 4-day fasted rats; it was found that protein, required for restoration of endogenous enzyme levels, did poorly restore T3-induction; however, either fat or carbohydrate, which poorly restored endogenous enzyme level, did restore T3-induction. These observations suggest that T3-induced LM-GPDH synthesis is independent of the dietary protein and that the diminution of T3-induction after fasting may primarily result from energy deficiency.
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