Abstract
Summary
The anemia produced in guinea pigs by dietary cholesterol led to a stimulation of erythropoietic activity with a proliferation of marrow cells which displaced the fat globules normally occupying the femoral marrow cavity. The triglyceride content decreased to half of its original level while the relative proportion of PL and cholesterol, on a dry, fat-free basis, remained unchanged. The proportion of linoleic acid in the remaining portion of TG decreased. Fractionation of the PL showed changes in their composition, particularly a decrease of the less polar components. The relationship of these changes in marrow to the changes observed in the peripheral blood requires further study.
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