Use of Human Diploid Cell Cultures for Primary Isolation of Respiratory Syncytial Virus. ∗

Abstract

Summary and Conclusion

Human embryo diploid and HEp-2 cell cultures were compared in respect to efficiency in isolating R. S. virus. Although initial manifestations of viral growth were evident somewhat earlier in HEp-2 than in diploid cells, isolation rates in the two types of cell cultures were not significantly different. Comparative infectivity titrations of original patient specimens in HEp-2 and WI-38 cell cultures suggested the possibility of a slight advantage in sensitivity for the latter cell.