Abstract
Summary
The effect of CPIB on ethanol-induced fatty liver was studied in 7 sets of group-fed rat litter mates. Total hepatic lipids averaged 50.4 mg/g higher in the animals fed ethanol alone than in those receiving ethanol plus CPIB (p<.02) with a corresponding difference in triglyceride of 53.3 mg/g (p<.001). Hepatic total lipid and triglycerides of the CPIB-ethanol group averaged 31.3 and 30.0 mg/g higher respectively (p<.01) than the control animals fed iso-caloric diets without ethanol. These findings indicate that CPIB significantly reduces triglyceride accumulation produced by prolonged ethanol intake; in the absence of ethanol hepatic triglycerides were not decreased.
Get full access to this article
View all access options for this article.