Abstract
Summary
Effect of insulin insufficiency on the transport of glucose in the intestinal cells was studied by incubation of small intestines of rats and guinea pigs in a medium containing glucose. Insulin deficiency was produced by injection of alloxan to rats and by feeding a scorbutogenic diet to guinea pigs. Concentrations of glucose in the intra-cellular water of the intestine incubated in glucose-saline were found higher in the intestines obtained from diabetic rats and from scorbutic guinea pigs as compared to normal. Insulin does not seem to have any direct role in the intracellular transport of glucose in the small intestine.
The Council of Scientific and Industrial Research, New Delhi, rendered financial assistance for the investigation.
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