Abstract
Conclusions
1. Clearance of small solutes from the mesentery is about 10 times as rapid as clearance of similar materials from muscle. 2. The ratio of clearances of colloidal to diffusible molecules from mesentery is about 2:3 at 29° and decreases to 1:2.5 at 43°C. 3. Experimentally induced increases of capillary filtration, and presumably lymph formation, increase clearance of colloidal material; those diminishing capillary nitration decrease clearance of colloids. 4. Movement of large molecules from injection depots may serve as an index of local lymph flow; clearance of small diffusible molecules measures flow through vessels capable of exchange. 5. Direct determinations of lymph flow rates from the “iliocolic” duct were found to be almost as great as flow from the thoracic duct. However, occlusion of the “iliocolic” duct diminishes thoracic duct flow by only a very small fraction. This paradox can be explained by the existence of connections between abdominal lymphatics and veins.
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