Abstract
Summary
The oxidation of intravenously administered carboxyl-labeled octanoic acid was estimated in 2 groups of rats by continuously measuring and recording the expired C14O2 in a carbon-14 analyzer. In 5 normal rats an average of 27.4% of the administered dose of radioactivity was recovered in the expired air in one hour. In 5 rats in which the liver had been excluded from the circulation an average of 23.7% was recovered. These results suggest that extra-hepatic tissues of the rat are capable of oxidizing octanoic acid at nearly the same rate as the intact animal.
Get full access to this article
View all access options for this article.