Abstract
Summary
When each of 32 different fractions, obtained from a human serum pool by electrophoresis, was added either to a bactericidal or a hemolytic serum reaction, inhibitory effects were found to be produced by some of the fractions. The bactericidal reaction, employing components present in “normal” human serum, was significantly inhibited by an excess of γ-globulins, and the hemolytic reaction by an excess of β-globulins. Inhibition of both reactions was also produced by an excess of serum fractions having the electrophoretic mobility of albumins. These findings are discussed in relation to quantitative and possibly qualitative differences in the serum components required for the bactericidal and hemolytic activities of serum.
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