Abstract
Summary
Following intravenous injection of inulin-C14OOH and inulin into a nephrectomized dog, the thoracic duct lymph was considerably higher than serum in specific activity, falling gradually to serum values. The fractionation of the smaller inulin-C14OOH molecules in lymph formation was thus similar to that observed in ultrafiltration through cellophane membranes, but it was quantitatively of insufficient magnitude to effect an observable decrease in serum inulin specific activity. It is suggested that the decrease in urine specific activity previously reported for the intact dog was due to a quicker uptake of inulin-C14OOH than non-labelled inulin by renal tissue.
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