Effect of Fluoride on Crystal Texture and Radiocalcium Uptake of Rat Bone

Abstract

Summary

Uptake of Ca⁴⁵ and hydroxy-apatite crystallinity as measured by degree of resolution of its X-ray diffraction pattern was compared in the femur, vertebra, and alveolar bone of rats given a drinking water containing either no fluoride or 50 ppm F for 14 months. Vertebra and alveolar bone contained significantly more Ca⁴⁵ than femur. Fluoride administration improved bone crystallinity but did not affect radiocalcium uptake. The possible effect of fluoride in bone accretion is discussed in relation to the above findings.