Abstract
Summary
The different fractions of plasma lipids were estimated in normal, scorbutic, insulin treated scorbutic and ascorbic acid supplemented scorbutic guinea pigs. Beta lipoprotein: alpha lipoprotein ratio, beta lipoprotein cholesterol, phospholipids and NEFA of plasma were increased and plasma triglycerides diminished in scorbutic animals. While insulin treatment of the scorbutic animals corrected only the plasma NEFA and triglyceride values, ascorbic acid supplementation brought back all these values to normal levels. Total plasma cholesterol did not change in scurvy. Ascorbic acid supplementation lowered the plasma cholesterol value below the value seen in normal guinea pigs, indicating hypocholesteremic effect of ascorbic acid. Neither insulin nor ascorbic acid seem to have specific roles in the metabolism of phospholipids.
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