Abstract
Summary
Clinically healthy subjects with elevated serum cholesterol levels were placed on a family diet pattern high in linoleic acid for a one-year period. The diet produced a highly significant decrease in serum cholesterol level (from 293 to 230 mg%). The greatest decrease occurred during the first several months; thereafter the serum cholesterol level fluctuated around 230 mg%. The diet produced a marked increase in percentage of linoleic acid in the serum cholesterol esters and triglycerides, with concomitant drops in percentages of saturated and oleic acids. It is concluded that such a dietary regimen for lowering the serum cholesterol level is practical for long periods.
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