Abstract
Summary
Effect of oxytocin, lactogen, and hydrocortisone acetate upon mammary gland involution was studied in rat. LGH retarded involution to a significant degree, by maintaining DNA 48% above control group. HCA at levels of 500 and 1000 μg retarded involution significantly when DNA was related to final BW. OXT by either subcutaneous or intraperitoneal administration was not effective in retarding involution. These hormones, however, appear to maintain some secretory activity of involuting mammary glands. Data also suggest OXT has little influence upon release of lactogen from anterior pituitary.
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