Abstract
Summary
Previous investigations have been concerned with the magnitude of the arteriovenous pressure difference when the blood flow is reduced to zero. The purpose of the present study was to extend earlier observations to include the mesenteric circulation. Isolated dog intestines were perfused with a pump-lung or dog-pump apparatus. Following cessation of arterial inflow the arteriovenous pressure difference steadily declined. As the rate of venous outflow approached zero, an arteriovenous pressure difference not significantly different from zero mm Hg was observed. Results suggest the importance of the role of the transmural pressure in interpretation of pressure-resistance relationships.
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