Abstract
Summary
Chicks bursectomized at hatching showed reduced antibody production to BSA, Brucella abortus antigen, and T2 coliphage, compared to controls. Chicks hatching from 19-nortestosterone-treated eggs, lacking the bursa of Fabricius, also showed a deficient homograft response to injections of adult homologous spleen cells manifested by splenomegaly, histologic changes characteristic of the graft-versus-host reaction, and signs of the runting syndrome.
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