Abstract
Summary
A study was made of the effects on oxygen consumption of halogenated salicylates in normal, thyroidectomized and hypermetabolic rats. It was found that 5-iodo-2-hydroxybenzoate and 5-bromo-2-hydroxyben-zoate increased the metabolism of rats under these 3 conditions. 4-Iodo-2-hydroxybenzoate increased the metabolism of normal and thyroidectomized rats. 5-Iodo-2-hydroxybenzoate and sodium salicylate increased the metabolism of normal mice. 3,5-Diiodo-2-hydroxybenzoate, 5-iodo-3-hydroxybenzoate and 3-hydroxybenzoate did not increase the metabolism of rats.
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