Abstract
Summary
Suspensions of leucocytes from 2 normal donors and 18 patients with various diseases, including 3 patients with congenital agammaglobulinemia were exposed to Sendai or measles virus and maintained in vitro for several days. Production of interferon occurred in 21 of 22 preparations. It is suggested that interferon-like substances may be liberated by leucocytes in vivo, after infection with some viruses and that production of interferon by leucocytes may provide a criterion for presence of non-cytopathic viruses.
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