Abstract
Summary
An analysis of the cervical mucus from 182 women randomly selected, revealed that 23.7% contained isohemagglutinins when a single specimen was examined but when more than one specimen was obtained the percentage rose to 63.4%. Type 0 women had agglutinins in their cervical secretions more frequently than either type A or type B women, and, in general, the titers were higher. There was no significant correlation between cervical secretion titers and serum hemagglutinin levels. The occurrence of antibodies in the cervical mucus seemed to be unaffected by the secretor type. Observations on multiple samples obtained from 41 women failed to suggest any correlation between antibody titer and phase of the menstrual cycle. These findings extend the data which earlier suggested the hypothesis of ABO selection at the gametic level as a factor in explaining the deficiency of certain types of offspring in ABO incompatible matings.
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