Abstract
Summary
Injection of insulin into intact rats increased the adrenaline contents of hearts and salivary glands. However, it decreased the adrenaline content of these tissues in animals from which the suprarenal medullae had been removed. The noradrenaline content of the heart was decreased after 7 to 11 hours of insulin action, but that of the salivary glands was unaltered. It is concluded that the increased amounts of adrenaline found in tissues of intact animals are due to the release of this catecholamine from the suprarenal medullae and its subsequent transport to and accumulation in the organs studied.
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