Encephalomyelitis and Pneumonitis in Hamsters Infected with Newcastle Disease Virus by Different Routes. ∗

Abstract

Summary

Hamsters injected intracere–brally or by peripheral routes with NDV developed encephalomyelitis and pneumonitis. The amount of virus required to produce infection varied for each route, being least by the intracerebral route and highest by the subcutaneous route. Virus was recovered from the brain but not from the lungs or blood in the prodromal stages. The manifestations and pathology of the resultant encephalomyelitis were similar irrespective of route of inoculation.