Abstract
Summary
Association of C14-labelled hydrocortisone with herpes virus-infected HeLa cells appeared nonspecific in that equal amounts of steroid were taken up at both 37°C and 4°C by noninfected as well as infected cells. The action of steroid on the cells resulted in a slight decrease in glucose uptake and a proportionally greater decrease in glucose stored. When steroid-treated cells were infected with virus, there was an increased uptake of glucose over that of virus-infected controls, and more glucose stored than in control cells treated with hydrocortisone suggesting that the action of steroid results in a partial return of stressed cells to more normal physiologic function.
Get full access to this article
View all access options for this article.