Abstract
Summary
Fluorescein labeled antibody staining of HEp-2 cell cultures infected with an inoculum of measles virus free of cell debris and other particulate matter revealed the presence of measles virus antigen in cells in metaphase, anaphase and telophase. Mitotic cells were shown to be readily recruited into syncytia induced by measles virus, both in absence and presence of colchicine. These observations contrast with the results of similar studies made in HEp-2 cell cultures infected with Herpes simplex virus and indicate that cells in different stages of the mitotic cycle are not uniformly susceptible to infection with different viruses, or even the same virus.
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