Abstract
Summary
Calcium and phosphorus content of connective tissue grown in rats implanted with polyvinyl alcohol sponges for 40 and 90 days was at high levels, which when correlated with histologic findings were indicative of salt formation. It appears that polyvinyl alcohol sponge has a greater tendency, from short term in vivo observations, to induce mineral deposits along its surfaces than other plastics tested. The data indicate a potential disadvantage to the usage of this plastic as a pliable prosthesis in human surgery.
The authors are indebted to Dr. Robert J. Boucek for helpful suggestions and to Mr. Al Latimer for histologic technical assistance.
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