Abstract
Summary
Experiments on rats indicate that the antimineralocorticoid steroid-spiro-lactone 3-(3 keto-7-thioacetoxy-17β-hydroxy-4-androsten-17α-yl) propanoic acid lactone—also known as SC-9420 or “Aldactone”®—offers considerable protection against induction of acute, infarct-like, often fatal myocardial necroses normally produced by fluorocortisol plus some Na-salts and stress, alone or in combination.
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