Abstract
Summary
1) Daily administration of 1 μg estradiol benzoate (EB) and 2 mg progesterone (P) to mature ovariectomized rats for 19 days resulted in mammary gland growth (mean total DNA/100 g) comparable to that of rats pregnant 18-20 days. Increasing the progesterone level to 10 mg daily has little further beneficial effect on mammary gland growth. 2) Variability in growth of experimentally developed gland was less than that of pregnant controls. 3) Total DNA appears to be a more reliable index of mammary gland growth when expressed as unit body weight.
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