Abstract
Summary
1) Interference between non-cytopathogenic Col SK virus and cytopathogenic EMC virus occurred on L cells in tissue culture, causing suppression of 0.7 to 2.63 logs of challenge virus depending on the dose of interfering virus used. 2) Interference also occurred between Col SK virus and poliomyelitis or Coxsackie Group B virus on HeLa cells, causing suppression of about 1 to 3 logs of challenge virus depending on the dose of interfering virus used. 3) The mechanism of the interference reaction is discussed.
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