Abstract
Summary
Exposure of Shigella dysenteriae organisms to bactericidal “normal” human sera in the presence of 20% sucrose results in survival of the bacteria and formation of wall-deficient spheroplasts. These “serum spheroplasts” differ from “penicillin spheroplasts” in several respects, including their susceptibility to osmotic shock. The relation of these observations to certain aspects of the phenomenon of bacterial lysis by serum has been discussed.
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