Abstract
Summary
1) Adult human and rabbit Fallopian tube fragments, which maintained in in vitro cultures their specific histological structure and coordinated vibratory activity, were submitted to infection with polio, adeno, bovine rhinotracheitis, herpes and other viruses. 2) The organized ciliated epithelium when compared with dedifferentiated epithelium in the same cultures showed in all cases a relative resistance to the cytopathic action of viruses, manifested by a marked delay in cell destruction, more pronounced in the case of bovine rhinotracheitis or polio and less marked in the case of herpes or vaccinia viruses. 3) This resistance could not be abolished either by immobilization of cilia with anesthetics or by treatment of cell surface with hyaluronidase or trypsin. 4) The meaning and implication of these data are discussed.
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