Abstract
Pentaerythritol Rosinate is the ester of rosin acids derived from Rosin with the polyol, pentaerythritol, used as a skin conditioning and viscosity increasing agent in mascaras. Animal data indicate little evidence of sub-chronic toxicity in feeding studies with Pentaerythritol Rosinate at concentrations up to 5%, or of chronic toxicity in feeding studies with the ingredient at 0.05%. No evidence of carcinogenicity was found in the chronic feeding studies. Historical data indicate that Pentaerythritol Rosinate may be used in cosmetics at concentrations up to 10%. The safety of use of this concentration of Pentaerythritol Rosinate has not been demonstrated. The data needed to evaluate safety include current concentration of use, source and method of manufacture, chemistry (UV spectral analysis, pH, and impurities), ocular irritation, human dermal irritation, sensitization, and photosensitization (only if the ingredient is found to absorb UVA or UVB radiation). It cannot be concluded that this ingredient is safe for use in cosmetic products until the cited data have been obtained and evaluated.