Cosmetic grade Petroleum Distillate consists predominantly of C10-C16 paraffinic, naphthenic, and isoparaffinic hydrocarbons. The Distillate is used in a variety of cosmetic products at concentrations up to 50%. Undiluted Petroleum Distillate had an acute oral LD50 in rats of >25 ml/kg. Subchronic animal tests on a formulation containing 41.75% Petroleum Distillate were uneventful. Moderate skin irritation and mild, transient eye irritation were observed in rabbits following a single exposure to undiluted Petroleum Distillate. Cosmetic formulations containing 29.2–55% Petroleum Distillate were generally nonirritating, nonsensitizing, and nonphotosensitizing to human skin. It is concluded that Petroleum Distillate, as characterized in the report, is safe as a cosmeticingredient at the current concentrations of use.
References
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55.
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56.
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57.
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58.
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59.
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60.
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61.
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62.
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63.
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64.
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65.
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66.
66. RESEARCH TESTING LABORATORIES, INC. (March 4, 1976). Submission of unpublished data by CTFA. Human subject patch study. Schwartz-Peck Prophetic Patch Test with UV Exposure. Two eye shadow creams containing 35 percent Petroleum Distillate. CTFA Code No. 2–29–21.
67.
67. CTFA. (October 14, 1974). Submission of unpublished data by CTFA. CIR safety data test summary response form. Mascara containing 53.25 percent Petroleum Distillate. RIPT with photopatch. CTFA Code No. 2–29–6.
