We present a case of a 48-year-old woman with a solitary fibrous tumor localized in the carotid bifurcation clinically simulating a chemodectoma. The tumor was composed of spindle cells with abundant intercellular collagen. These spindle cells were positive for CD34 and negative for chromogranin, S-100 protein, NSE, GFAP, and cytokeratin. This is the first solitary fibrous tumor reported in this location, in the English literature.
1. Sout AP, Murray MR. Localized pleural mesothelioma. Investigation of its characteristics and histogenesis by the method of tissue culture. Arch Pathol34:50-64, 1951
2.
2. Goodlad JR, Fletcher CDM. Solitary fibrous tumor of unusual sites: Analysis of a series. Histopathology19:515-522, 1991
3.
3. Suster S, Nascimento AG, Miettinen M, Sickel JZ, Moran CA. Solitary fibrous tumor of soft tissue. Am J Surg Pathol19:1257-1266, 1995
4.
4. van de Rijn M, Rouse RV. CD34. A review. Appl Immunohistochem2:71-80, 1994
5.
5. Ortiz Hidalgo C, de León Bjorge B, de la Vega G. Utilidad diagn6stico del CD-34 en patologia quirurgica. Patologia35:261-267, 1997
6.
6. Wright-Browne V, McClain KL, Talpaz M, Ordofiez N, Estrov Z. Physiology and pathophysiology of dendritic cells. Hum Pathol28:563-579, 1997
7.
7. Enzinger FM, Weiss SW. Paragangliomas. In Soft tissue tumors, 3rd ed.Mosby, St. Louis, pp. 965-990, 1995
8.
8. Westra WH, Gerald WL, Rosai J. Solitary fibrous tumor. Consistent CD34 immunoreactivity and occurrence in the orbit. Am J Surg Pathol18: 992-998, 1994
9.
9. Weiss S, Nickoloff B. CD34 is expressed by a distinctive cell population in peripheral nerve, nerve sheath tumors and related lesions. Am J Surg Pathol17:1039-1045, 1993
10.
10. El-Nagar AK, Ro JA, Ayala AG, Ward R, Ordofiez NG. Localized fibrous tumor of the serosal cavities. Immunohistochemical, electron-microscopic and flow cytometric DNA study. Am J Clin Pathol92: 703-704, 1987
11.
11. Fukunaga M, Nikaido T. Solitary fibrous tumor of the renal peripelvis. Histopathology30:451-456, 1997