Research on Chronic Fatigue Syndrome has not identified a definitive cause or treatment but psychological aspects have been noted.
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References
1.
AbbeyS. E.GarfinkelP. E. (1990) Chronic fatigue syndrome and the psychiatrist. Canadian Journal of Psychiatry, 35, 625–633.
2.
AbbeyS. E.GarfinkelP. E. (1991) Neurasthenia and chronic fatigue syndrome: The role of culture in the making of a diagnosis. American Journal of Psychiatry, 148, 1638–1646.
3.
AchesonE. D. (1959) The clinical syndrome variously called benign myalgic encephalomyelitis, Iceland disease, and epidemic neuromyasthenia. American Journal of Medicine, 26, 569–595.
4.
A new clinical entity? (1956) Lancet, 1 (May 26), 789–790.
5.
BarnesD. M. (1986) Mystery disease at Lake Tahoe challenges virologists and clinicians. Science, 234, 541–542.
6.
BartleyS. H. (1981) Fatigue. Perceptual and Motor Skills, 53, 958.
7.
BehanP. O.BehanW. M.HorrobinD. (1990) Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurologica Scandinavica, 82, 209–216.
8.
BridgesK. W.GoldbergD. P. (1984) Psychiatric illness in inpatients with neurological disorders: Patients' views on discussion of emotional problems with neurologists. British Medical Journal, 289, 656–658
9.
BridgesK. W.GoldbergD. P. (1985) Somatic presentation of DSM-III psychiatric disorders in primary care. Journal of Psychosomatic Research, 29, 563–569.
10.
BroadbentD. E. (1979) The Society's lecture 1979: Is a fatigue test now possible?Ergonomics, 22, 1277–1290.
11.
BuchwaldD.KomaroffA. L. (1991) Review of laboratory findings for patients with Chronic Fatigue Syndrome. Reviews of Infectious Diseases, 13 (Suppl. 1), SI 2–8.
12.
BuchwaldD.SullivanJ. L.KomaroffA. L. (1987) Frequency of “chronic active Epstein-Barr virus infection” in a general medical practice. Journal of the American Medical Association, 257, 2303–2307.
13.
CadieM.NyeF. J.StoreyP. (1976) Anxiety and depression after infectious mononucleosis. British Journal of Psychiatry, 128, 559–561.
14.
CaligiuriM.MurrayC.BuchwaldD.LevineH.CheneyP.PetersonD.KomaroffA. L.RitzJ. (1987) Phenotypic and functional deficiency of natural killer cells in patients with chronic faugue syndrome. Journal of Immunology, 139, 3306–3313.
15.
ChaoC. C.GallagherM.PhairJ.PetersonP. K. (1990) Serum neopterin and interleukin-6 levels in chronic fatigue syndrome. Journal of Infectious Disease, 162, 1412–1413.
16.
CheneyP. (1991) The Cheney clinic, P. A.The CFIDS Chronicle, (Fall), 5–7.
17.
CherfasJ. (1990) Chronic fatigue as chameleon. Science, 249, 1240.
18.
CottonP. (1991) Treatment proposed for chronic fatigue syndrome: Research continues to compile data on disorder. Journal of the American Medical Association, 266, 2667–2668.
19.
CoxI. M.CampbellM. J.DowsonD. (1991) Red blood cell magnesium and chronic fatigue syndrome. Lancet, 337, 757–760.
20.
DaleJ. K.StrausS. E.AblashiD. V.SalahuddinZ. S.GalloR. C.NishibeY.InoueY. K. (1989) The Inoue-Melnick virus, human herpes virus type 6, and the chronic fatigue syndrome. Annals of Internal Medicine, 110, 92–93.
21.
DavidA. S.WesselyS.PelosiA. J. (1988) Postviral fatigue syndrome: Time for a new approach. British Medical Journal, 296, 696–699.
22.
DawsonJ. (1987) Royal Free disease: Perplexity continues. British Medical Journal, 294, 327–328.
23.
DeFreitasE.HilliardB.CheneyP. R.BellD. S.KiggunduE.SankeyD.WroblewskaZ.PalladinoM.WoodwardJ. P.KoprowskiH. (1991) Retroviral sequences related to human T-lymphotropic virus type II in patients with chronic fatigue immune dysfunction syndrome. Proceedings of National Science, 88, 2922–2926.
24.
DillonM. J.MarshallW. C.DudgeonJ. A.SteigmanA. J. (1974) Epidemic neuromyasthenia: Outbreak among nurses at a children's hospital. British Medical Journal, 1, 301–305.
25.
Editorial. (1990) Chronic fatigue syndrome—false avenues and dead ends. Lancet, 337, 331–332.
26.
GalpineJ. F.MacraeA. D. (1953) An outbreak of benign meningo-encephalitis: Isolation of Coxsackie virus. Lancet, 1, 372–376.
27.
GantzN. M.HolmesG. P. (1989) Treatment of patients with chronic fatigue syndrome. Drugs, 38, 855–862.
28.
GoldD.BowdenR.SixbeyJ.RiggsR.KatonW. J.AshleyR.ObrigewitchR.CoreyL. (1990) Chronic fatigue: A prospective clinical and virological study. Journal of the American Medical Association, 264, 48–53.
29.
GoldbergD. P.BlackwellB. (1970) Psychiatric illness in general practice: A detailed study using a new method of case identification. British Medical Journal, 2, 439–443.
30.
GoodnickP. J. (1990) Bupropion in chronic fatigue syndrome. American Journal of Psychiatry, 147, 1091. (Letter to Editor)
31.
GreenbergD. B. (1990) Neurasthenia in the 1980s: Chronic mononucleosis, chronic fatigue syndrome, and anxiety and depressive disorder. Psychosomatics, 31, 129–137.
32.
HartnellL. (1987) Post-viral fatigue syndrome: A canker in my brain. Lancet, 1, 910.
33.
HarveyW. T. (1989) A flight surgeon's personal view of an emerging illness. Aviation, Space, and Environmental Medicine, 60, 1199–1201.
34.
HellingerW. C.SmithT. F.Van ScoyR. E.SpitzerP. G.ForgaesP.EdsonR. S. (1988) Chronic fatigue syndrome and the diagnostic utility of antibody to Epstein-Barr Virus early antigen. Journal of the American Medical Association, 260, 971–973.
35.
HendersonD. A.ShelokovA. (1959) Epidemic neuromyasthenia—clinical syndrome?New England Journal of Medicine, 260, 757–764.
36.
HickieI.LloydA.WakefieldD. (1991) Chronic fatigue syndrome and depression. Lancet, 337, 922–923. (Letter to Editor)
37.
HickieI.LloydA.WakefieldD.ParkerG. (1990) The psychiatric status of patients with chronic fatigue syndrome. British Journal of Psychiatry, 156, 534–540.
38.
HolmesG. P.KaplanJ. E.GantzN. M.KomaroffA. L.SchonbergerL. B.StrausS. E.JonesJ. F.DuboisR. E.Cunningham-RundlesC.PahwaS.TosatoG.ZegansL. S.PurtiloD. T.BrownN.SchooleyR. T.BrusI. (1988) Chronic fatigue syndrome: A working case definition. Annals of Internal Medicine, 108, 387–389.
39.
HolmesG. P.KaplanJ. E.StewardJ. A.HuntB.PinskyP. F.SchonbergerL. B. (1987) A cluster of patients with a chronic mononucleosis-like syndrome: Is Epstein-Barr virus the cause?Journal of the American Medical Association, 257, 2297–2302.
40.
HullerR. F.MoserR. J.III, (1990) Chronic fatigue: Psyche or sleep?Archives of Internal Medicine, 150, 1116–1117. (Letter to Editor)
41.
JonesJ. F.StrausS. E. (1987) Chronic Epstein-Barr virus infection. Annual Review of Medicine, 38, 195–209.
42.
JonesJ. F.WilliamsM.SchooleyR. T.RobinsonC.GlaserR. (1988) Antibodies to Epstein-Barr virus-specific DNase and DNA polymerase in the chronic fatigue syndrome. Archives of Internal Medicine, 148, 1957–1960.
43.
KaslS. V.EvansA. S.NiedermanJ. C. (1979) Psychosocial risk factors in the development of infectious mononucleosis. Psychosomatic Medicine, 41, 445–466.
44.
KaslowJ. E.RuckerL.OnishiR. (1989) Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Archives of Internal Medicine, 149, 2501–2503.
45.
KendellR. E. (1991) Chronic fatigue, viruses, and depression. Lancet, 337, 160–162.
46.
KennedyH. G. (1987) Fatigue and fatigability. Lancet, 1, 1145.
47.
KomaroffA. L.BuchwaldD. (1991) Symptoms and signs of chronic fatigue syndrome. Reviews of Infectious Diseases, 13 (Suppl. 1), S8–11.
48.
KomaroffA. L.WangS-P.LeeJ.GraystonJ. T. (1992) No association of chronic chlamydia pneumoniae infection with chronic fatigue syndrome. Journal of Infectious Diseases, 165, 184.
49.
KroenkeK.WoodD. R.MangelsdorffD.MeierN. J.PowellJ. B. (1988) Chronic fatigue in primary care: Prevalence, patient characteristics, and outcome. Journal of the American Medical Association, 260, 929–934.
50.
KruesiM. J. P.DaleJ.StrausS. E. (1990) Psychiatric diagnoses in patients who have chronic fatigue syndrome. Journal of Clinical Psychiatry, 50(2), 53–56.
51.
LandayA. L.JessopC.LennetteE. T.LevyJ. A. (1991) Chronic fatigue syndrome: Clinical condition associated with immune activation. Lancet, 338, 707–711.
52.
LevineP. H.KruegerR. F.StrausS. E. (1989) The postviral chronic fatigue syndrome: A round table. Journal of Infectious Diseases, 160, 722–724.
53.
LloydA.HickieA.BrockmanA.DwyerJ.WakefieldD. (1991) Cytokine levels in serum and cerebrospinal fluid in patients with chronic fatigue syndrome and control subjects. Journal of Infectious Diseases, 164, 1023–1024. (Letter to Editor)
54.
LloydA. R.HalesJ. P.GandeviaS. C. (1988) Muscle strength, endurance and recovery in the post-infection fatigue syndrome. Journal of Neurology, Neurosurgery, and Psychiatry, 51, 1316–1322.
55.
LloydA. R.WakefieldD.BoughtonC.DwyerJ. (1988) What is myalgic encephalomyelitis?Lancet, 1, 1286–1288. (Letter to Editor)
56.
ManuP.LaneT. J.MatthewsD. A. (1988) The frequency of the chronic fatigue syndrome in patients with symptoms of persistent fatigue. Annals of Internal Medicine, 109, 554–556.
57.
ManuP.LaneT. J.MatthewsD A, (1989) Somatization disorder in patients with chronic fatigue. Psychosomatics, 30, 388–395.
58.
ManuP.MatthewsD. A.LaneT. J. (1988) The mental health of patients with a chief complaint of chronic fatigue: Prospective evaluation and follow-up. Archives of Internal Medicine, 148, 2213–2217.
59.
ManuP.MatthewsD. A.LaneT. J.TennenH.HesselbrockV.MendolaR.AffleckG. (1989) Depression among patients with a chief complaint of chronic fatigue. Journal of Affective Disorders, 17, 165–172.
60.
MartinW. J. (1991) Spumavirus associated myalgic encephalomyelopathy. The CFIDS Chronicle, (Fall), 2–4.
61.
McConnellJ. (1945) An epidemic of pleurodynia with prominent neurologic symptoms and no demonstrable cause. American Journal of Medical Science, 209, 41–48.
62.
McEvedyC. P.BeardA. W. (1973) A controlled follow-up of cases involved in an epidemic of “Benign myalgic encephalomyelitis.”British Journal of Psychiatry, 122, 141–150.
63.
MitchellC. A. (1986) Generalized chronic fatigue in the elderly: Assessment and intervention. Journal of Gerontological Nursing, 12(4), 19–23.
64.
MontgomeryG. K. (1983) Uncommon tiredness among college undergraduates. Journal of Consulting and Clinical Psychology, 51, 517–525.
65.
MorteS.CastillaA.CiveiraM. P.SerranoM.PrietoJ. (1989) Production of interleukin-1 by peripheral blood mononuclear cells in patients with chronic fatigue syndrome. Journal of Infectious Diseases, 159, 362. (Letter to Editor)
66.
NelsonE.KirkJ.McHugoG.DouglassR.OhlerJ.WassonJ.ZubkoffM. (1987) Chief complaint fatigue: A longitudinal study from the patient's perspective. Family Practice Research Journal, 6, 175–188.
67.
Outbreak at the Royal Free. (1955) Lancet, 2, 351.
68.
PalcaJ. (1991) On the track of an elusive disease. Science, 254, 1726–1728.
69.
PayneC. B.Jr.SloanH. E. (1989) Pulmonary function and chronic fatigue syndrome. Annals of Internal Medicine, 111, 860. (Letter to Editor)
70.
PoteliakhoffA. (1981) Adrenocortical activity and some clinical findings in acute and chronic fatigue. Journal of Psychosomatic Research, 25, 91–95.
ReadR.SpickettG.HarveyJ.EdwardsA. J.LarsonH. E. (1988) IgGI subclass deficiency in patients with chronic fatigue syndrome. Lancet, 1, 241–242. (Letter to Editor)
73.
RiddleP. K. (1982) Chronic fatigue and women: A description and suggested treatment. Women and Health, 7(1), 37–47.
74.
RobinsL. N.HelzerJ. E.CroughanJ.WilliamsJ. B. W.SpitzerR. L. (1981) NIMH Diagnostic Interview Schedule. Rockville, MD: Department of Health and Human Services, National Institute of Mental Health.
75.
RodinG.VoshartK. (1986) Depression in the medically ill: An overview. American Journal of Psychiatry, 143, 696–705.
76.
ShelokovA.HabelK.VerderE.WelshW. (1957) Epidemic neuromyasthenia: An outbreak of poliomyelitis-like illness in student nurses. New England Journal of Medicine, 257, 345.
77.
ShorterE. (1992) A history of psychosomatic illness in the modern era. New York: Free Press.
78.
SkolnickA. A. (1991) Chronic fatigue syndrome. Journal of the American Medical Association, 266, 2336.
79.
StrausS. E. (1987) EB or not EB—that is the question. Journal of the American Medical Association, 57, 2335–2336.
80.
StrausS. E. (1991) History of Chronic Fatigue Syndrome. Reviews of Infectious Diseases, 13 (Suppl. 1), S2–7.
81.
StrausS. E.DaleJ. K.PeterJ. B.DinarelloC. A. (1989) Circulating lymphokine levels in the chronic fatigue syndrome. Journal of Infectious Diseases, 160, 1085. (Letter to Editor)
82.
StrausS. E.DaleJ. K.TobiM.LawleyT.PrebleO.BlaeseR. M.HallahanC.HenleW. (1988) Acyclovir treatment of the chronic fatigue syndrome: Lack of efficacy in a placebo-controlled trial. New England Journal of Medicine, 319, 1692–1698.
83.
StrausS. E.DaleJ. K.WrightR.MetcalfeD. D. (1988) Allergy and the chronic fatigue syndrome. Journal of Allergy and Clinical Immunology, 81, 791–795.
84.
StrausS. E.TosatoG.ArmstrongG.LawleyT.PrebleO. T.HenleW.DaveyR.PearsonG.EpsteinJ.BrusI.BlaeseR. M. (1985) Persisting illness and fatigue in adults with evidence of Epstein-Barr virus infection. Annals of Internal Medicine, 102, 7–16.
85.
SubiraM. L.CastillaA.CiveiraM-P.PrietoJ. (1989) Deficient display of CD 3 on lymphocytes of patients with chronic fatigue syndrome. Journal of Infectious Diseases, 160, 165. (Letter to Editor)
86.
SugarmanJ. R.BergA. O. (1984) Evaluation of fatigue in a family practice. Journal of Family Practice, 19, 643–647.
87.
SwansonD. W.MooreG. L.NobregaF. T. (1978) Family history of alcoholism in patients with chronic fatigue. Journal of Clinical Psychiatry, 39, 754–755.
88.
SwartzM. N. (1988) The chronic fatigue syndrome—one entity or many?New England Journal of Medicine, 319, 1726–1728.
89.
WesselyS. (1990) Old wine in new bottles: Neurasthenia and ME. Psychological Medicine, 20, 35–53.
90.
WesselyS.PowellR. (1989) Fatigue syndromes: A comparison of chronic “postviral” fatigue with neuromuscular and affective disorders. Journal of Neurology, Neurosurgery and Psychiatry, 52, 940–948.