Abstract
This apparatus was designed to administer chronic and high-level doses of clinical drugs (e.g., hydrochlorothiazide, allopurinol, clofibrate) to primates by suspending the drugs in a liquid reinforcer in order to assess their effects on operant baselines. Since nausea, drowsiness, and other common side effects might well be more pronounced in experimental vibration and altered gravity—conditions of interest to flying personnel—the apparatus was designed to be able to withstand such conditions without degradation of the reinforcement delivery mechanism.
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