We present the case of a 21-year-old young lady with Wilson's disease, asymptomatic at first and consequently declining prophylaxis with chelating agents, who presented years after her diagnosis was made with multiple motor and neuropsychiatric manifestations of the disease, causing extensive morbidity and a major decrease in her quality of life. Following extensive education and supportive therapy, she showed conviction in the need for therapy. On close follow-up she continues to show compliance with appointments, the prescribed chelating agents, and psychotropic medication.
SternliebIScheinbergIH. Prevention of Wilson's Disease in asymptomatic patients. New England Journal of Medicine1968; 278(7): 352–359
7.
RobertsESchliskyM. A practice guideline on Wilson Disease. Hepatology2003; 37(7): 1475–1492
8.
RohJKLeeTGWieBALeeSBParkSHChangKH. Initial and follow-up brain MRI findings and correlation with the clinical course in Wilson's Disease. Neurology1994; 44(6): 1064–1068
9.
MillerNH. Compliance with treatment regimens in chronic asymptomatic diseases. American Journal of Medicine1997; 102 (2A): 43–49
10.
AlaASchilskyM. Wilson Disease: Pathophysiology, diagnosis, treatment, and screening. Clinics in Liver Disease2004; 8(4): 787–805
