Field cases in which animals exhibit symptoms of feed refusal, mouth and lip irritation, and internal hemorrhage are common. These cases have been associated with the presence of scirpene toxins in feeds. The Chemistry Laboratory at the Iowa State University, Diagnostic Laboratory, has used existing methodology, and thin layer chromatography, gas chromatography, and mass spectroscopy to attempt to determine if known scirpene toxins were involved in a diagnostic laboratory case. Chicken embryo toxicity of the extracts, field desorption and chemical ionization indicate the presence of some known scirpene toxins as well as unknown compounds.
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RinehartK. L. and CookeJ. C.Jr., J. Antibiot.27, 1 (1974).
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FalesH. N. and DamicoJ. A., Mass Spectrometry Applied to the Identifications of Pesticides and Metabolites, Pestic. Symp. Am. Chem. Soc. North Dakota State University, Fargo (FDA, Washington, DC, 1972).
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