Multilayer Enhanced Gold Film over Nanostructure Surface-Enhanced Raman Substrates

Abstract

We have developed a novel class of gold multilayer, surface-enhanced Raman scattering (SERS) substrates that are capable of enhancing SERS signals by 15.3-fold over conventional gold film over nanostructure (GFON) SERS substrates, making them comparable in sensitivity to optimized silver film over nanostructure (SFON) substrates, while providing the long-term stability obtained from gold. They are fabricated by depositing 10 Å thick silver oxide islands on conventional GFON substrates, followed by deposition of a second continuous gold layer. The silver oxide layer acts as a dielectric spacer between the two continuous gold films and produces significantly enhanced SERS signals, as compared to optimized single layer substrates of the same geometry or comparable substrates prepared by deposition of silver islands that are not oxidized. In addition to the enhanced sensitivity of these multilayer substrates, they also exhibit long SERS active shelf-lives (i.e., months), with no measurable degradation in SERS enhancement, and relative standard deviations in SERS enhancement of less than 5.2% across the substrate's surface.

Keywords

Surface-enhanced Raman spectroscopy SERS Multilayer Metal films Nanostructure

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References

Vo-Dinh

Allain

L. R.

and Stokes

D. L

, J. Raman Spectrosc. 33, 511 (2002).

Giese

and McNaughton

, J. Phys. Chem. B 106, 1461 (2002).

Vo-Dinh

and Stokes

D. L

, Biomedical Photonics Handbook 1, 64 (2003).

Alexander

T. A.

Pellegrino

P. M.

and Gillespie

J. B

, Appl. Spectrosc. 57, 1340 (2003).

Sun

Alexander

T. A.

and Cullum

B. M

, Proc. SPIE-Int. Soc. Opt. Eng. 5795, 8 (2005).

Jarvis

R. M.

and Goodacre

, Anal. Chem. 76, 40 (2004).

Zhang

Young

M. A.

Lyandres

and Duyne

R. P. V

, J. Am. Chem. Soc. 127, 4484 (2005).

Weaver

M. J.

, J. Raman Spectrosc. 33, 309 (2002).

Taranenko

Alarie

J.-P.

Stokes

D. L.

and Vo-Dinh

, J. Raman Spectrosc. 27, 379 (1996).

10.

Patel

P. H.

and Cullum

B. M

, Proc. SPIE-Int. Soc. Opt. Eng. 5588, 87 (2004).

11.

Yonzon

C. R.

Stuart

D. A.

Zhang

McFarland

A. D.

Haynes

C. L.

and Duyne

R. P. V

, Talanta 67, 438 (2005).

12.

Kneipp

Rice

W. L.

and Kneipp

, Anal. Chem. 77, 2381 (2005).

13.

Drachev

V. P.

Thoreson

M. D.

Khaliullin

E. N.

Davisson

V. J.

and Shalaev

V. M

, J. Phys. Chem. B 108, 18046 (2004).

14.

Keating

C. D.

Kovaleski

K. K.

and Natan

M. J

, J. Phys. Chem. B 102, 9414 (1998).

15.

Nie

and Emory

S. R

, Science (Washington, D.C.) 275, 1102 (1997).

16.

Otto

, in Light scattering in solids IV: Electronic Scattering, Spin Effects, SERS, and Morphic Effects, Cardona

and Guntherodt

, Eds. (Springer-Verlag, Berlin, Heidelberg, New York, 1984), Vol. 54, p. 289.

17.

Moskovits

, Rev. Mod. Phys. 57, 783 (1985).

18.

Birke

R. L.

and Lombardi

J. R

, in Spectroelectrochemistry, Gale

R. J.

Ed. (A Division of Plenum Publishing Corporation, New York, 1988), p. 263.

19.

Zeman

E. J.

and Schatz

G. C

, J. Phys. Chem. 91, 634 (1987).

20.

Fleischmann

Hendra

P. J.

and McQuillan

A. J

, Chem. Phys. Lett. 26, 163 (1974).

21.

Zheng

and Lu

, J. Phys. Chem. B 106, 1019 (2002).

22.

Hoogvliet

J. C.

Dijksma

Kamp

and Van Bennekom

W. P

, Anal. Chem. 72, 2016 (2000).

23.

Michota

and Bukowska

, J. Raman Spectrosc. 34, 21 (2003).

24.

Leopold

and Lendl

, J. Phys. Chem. B 107, 5723 (2003).

25.

Lyon

L. A.

Musick

M. D.

and Natan

M. J

, Anal. Chem. 70, 5177 (1998).

26.

Chen

M. C.

Tsai

S. D.

Chen

M. R.

S. Y.

W.-H.

and Lee

K. C

, Phys. Rev. B 51, 4507 (1995).

27.

Boo

D. W.

W. S.

Kim

M. S.

Kim

and Lee

H.-C

, Chem. Phys. Lett. 120, 301 (1985).

28.

and Cotton

T. M

, Anal. Chem. 58, 3159 (1986).

29.

Kwon

C. H.

Boo

D. W.

Hwang

H. J.

and Kim

M. S

, J. Phys. Chem. B 103, 9610 (1999).

30.

Litorja

Haynes

L. C.

Haes

J. A.

Jensen

R. T.

and Van Duyne

P. R

, J. Phys. Chem. B 105, 6907 (2001).

31.

Bello

M. J.

Stokes

L. D.

and Vo-Dinh

, Anal. Chem. 61, 1779 (1989).

32.

Bello

M. J.

Stokes

L. D.

and Vo-Dinh

, Appl. Spectrosc. 43, 1325 (1989).

33.

Alak

A. M.

and Vo-Dinh

, Anal. Chem. 61, 656 (1989).

34.

Xue

and Dong

, Anal. Chem. 63, 2393 (1991).

35.

Kneipp

Kartha

V. B.

Manoharan

Deinum

Itzkan

Dasari

R. R.

and Feld

M. S

, Phys. Rev. E 57, R6281 (1998).

36.

Kneipp

Wang

Kneipp

Perelman

L. T.

Itzkan

Dasari

R. R.

and Feld

M. S

, Phys. Rev. Lett. 78, 1667 (1997).

37.

Haynes

C. L.

and Duyne

R. P. V

, J. Phys. Chem. B 107, 7426 (2003).

38.

McFarland

A. D.

Young

M. A.

Dieringer

J. A.

and Duyne

R. P. V

, J. Phys. Chem. B 109, 11279 (2005).

39.

Vo-Dinh

Hiromoto

M. Y. K.

Begun

G. M.

and Moody

R. L

, Anal. Chem. 56, 1667 (1984).

40.

Schueler

P. A.

Ives

J. T.

Delacroix

Lacy

W. B.

Becker

P. A.

Caldwell

K. D.

Drake

and Harris

J. M

, Anal. Chem. 65, 3117 (1993).

41.

Mullen

K. I.

Wang

D.-X.

Crane

L. G.

and Carron

K. T

, Spectroscopy 7, 24 (1992).

42.

Leverettee

L. C.

Shubert

A. V.

Wade

L. T.

Varazo

and Dluhy

A. R

, J. Phys. Chem. B 106, 8747 (2002).

43.

Mulvaney

S. P.

Natan

M. J.

and Keating

C. D

, J. Raman Spectrosc. 34, 163 (2003).

44.

and Cullum

B. M

, Appl. Spectrosc 59, 410 (2005).

45.

Stuart

D. A.

Yonzon

C. R.

Zhang

Lyandres

Shah

N. C.

Glucksberg

M. R.

Walsh

J. T.

and Duyne

R. P. V

, Anal. Chem. 77, 4013 (2005).

46.

Lacy

W. B.

Olson

L. G.

and Harris

J. M

, Anal. Chem. 71, 2564 (1999).