Drug Interaction 2. How drugs interact

Goodman L. S. and Gilman A. : The Pharmacological Basis of Therapeutics. MacMillan Co. New York, p. 2, 1965.

Ibid. p. 17

Ibid. p. 3

Ibid. p. 4

Ibid. p. 10

MacGregor A. G. : Clinical Effects of Interaction Between Drugs. Review of Points at Which Drugs Can Interact, Proc. Roy. Soc. Med. 58:943 (Nov.) 1965.

Milne M.D. : Clinical Effects of Interaction Between Drugs. Influence of Acid-Base Balance on Efficacy and Toxicity of Drugs, Proc. Roy. Soc. Med. 58:961 (Nov.) 1965. References Quoted In Milne (7. Above)

Waddell W. J. and Butler T. C. : The Distribution and Excretion of Phenobarbital, J. Clin. Invest. 36:1217 (Aug.) 1957.

Payne J. P. and Rowe G. G. : The Effects of Mecamylamine on the Cat as Modified by the Administration of Carbon Dioxide, Brit. J. Pharmacol. 12:555 (Dec.) 1957.

Blackman J. G. and Ray C .: Actions of Mecamylamine, Dimecamine, Pempidine and Their Two Quaternary Metho-salts at the Neuromuscular Junction, Brit. J. Pharmacol. 22:56 (Feb.) 1964.

Brodie B. B. : Clinical Effects of Interaction Between Drugs. Displacement of One Drug by Another from Carrier or Receptor Sites, Proc. Roy. Soc. Med. 58:946 (Nov.) 1965.

Christensen L. K. Hansen J. M. and Kristensen M. : Sulphaphenazole-Induced Hypoglycemic Attacks in Tolbutamide-Treated Diabetics, Lancet 2:1298 (Dec. 21) 1963.

Eisen M. J. : Combined Effect of Sodium Warfarin and Phenylbutazone, J. Am. Med. Assoc. 189:64 (July 6) 1964.

Dixon R. L. Hendersen T. J. and Rall D. P. : Fed. Proc. 24:454, 1965.

Zubrod C. G. Kennedy T. J. and Shannon J. A. : J. Clin. Invest. 27:114, 1948.

Odell G. B. : Studies on Kernicterus. I. The Protein Binding of Bilirubin, J. Clin. Invest. 38:823 (May) 1959.

Silverman W. A. : A Difference in Mortality Rate and Incidence of Kernicterus among Premature Infants Allotted to Two Prophylactic Anti-bacterial Regimens, Pediatrics 18:614 (Oct.) 1956.

Hench P. S. : Reversibility of Certain Rheumatic and Non-rheumatic Conditions by Use of Cortisone or of Pituitary Adrenocorticotropic Hormone, Ann. Internal Med. 36:1 (Jan.) 1952.

Maickel R. P. Miller F. P. and Brodie B. B. : Pharmacologist 1:182, 1965.

Goodman L.S. and Gilman A. : The Pharmacological Basis of Therapeutics, MacMillan Co., New York, 1965, p. 17.

Ibid. p. 14

Burns J. J. and Conney A. H. : Clinical Effects of Interaction Between Drugs. Enzyme Stimulation and Inhibition in the Metabolism of Drugs, Proc. Roy. Soc. Med. 58:955 (Nov.) 1965.

Fouts J. R. and Rogers L. A. : Morphological Changes in the Liver Accompanying Stimulation of Microsomal Drug-Metabolizing Enzyme Activity by Phenobarbital, Chlordane, Benzpyrene or Methylcholanthrene in Rats. J. Pharmacol. Exptl. Therap. 147:112 (Jan.) 1965.

Remmer H. and Merker H. J. : [Enzyme Induction and Increase of Endoplasmic Reticulum in Liver Cells during Phenobarbital (Luminal) Therapy], Klin. Wochschr. 41:276 (Mar. 15) 1963.

Conney A. H. Davison C. Gastel R. and Burns J. J. : Adaptive Increases in Drug-Metabolizing Enzymes Induced by Phenobarbital and Other Drugs, J. Pharmacol. Exptl. Therap. 130:1, 1960.

Cucinell S. A. Conney A. H. Sansur M. and Burns J. J. : Drug Interactions in man. I. Lowering Effect of Phenobabital on Plasma Levels of Bishydroxycoumarin (Dicumarol) and Diphenylhydantoin (Dilantin) Clin. Pharmacol. Therap. 6:420, 1965.

Dayton P. G. : J. Clin. Invest. 40:1797, 1961.

Busfield D. Child K. J. and Tomich E. G. : An Effect of Phenobarbitone on Griseofulvin Metabolism in the Rat, Brit. J. Pharmacol. 22:137 (Feb). 1964.

Busfield D. : An Effect of Phenobarbitone on Blood Levels of Griseofulvin in Man, Lancet 2:1042 (Nov. 16) 1963.

Chen W. : Life Sci. 2:35, 1962.

Hart L. G. Shultice R. W. and Fouts J. R. : Stimulatory Effects of Chlordane on Hepatic Microsomal Drug Metabolism in the Rat, Toxicol. Appl. Pharmacol. 5:371 (May) 1963.

Burns J. J. : Application of Drug Metabolism to Drug Toxicity Studies, Ann. N.Y. Acad. Sci. 123:273 (Mar. 12) 1965.

Conney A. H. : Drug-Induced Changes in Steroid Metabolism, Ann. N.Y. Acad. Sci. 123:98 (Mar. 12) 1965.

Gillette J. R. : Fortschr. Arzneimittel-Forsch. 6:11, 1963.

Fox S. L. : Potentiation of Anticoagulants Caused by Pyrazole Compounds, J. Am. Med. Assoc. 188:320 (Apr. 20) 1964.

Weiner M. : Fed. Proc. 24:153, 1965.

Serrone D. M. and Fujimotu J. M. : The Effect of Certain Inhibitors in Producing Shortening of Hexobarbital Action, Biochem. Pharmacol. 11:609 (July) 1962.

Kato R. Chiesara E. and Vassanelli P. : Further Studies on the Inhibition and Stimulation of Microsomal Drug-Metabolizing Enzymes of Rat Liver by Various Compounds, Biochem. Pharmacol. 13:69 (Jan.) 1964.

Goodman L. S. and Gilman A. : The Pharmacological Basis of Therapeutics, MacMillan Co., New York, 1965, p. 12.

Ibid. p. 13

Ibid. p. 14

Sjögvist F. : Clinical Effects of Interaction Between Drugs. Psychotropic Drugs (2). Interaction Between Monoamine Oxidase (MAO) Inhibitors and Other Substances, Proc. Roy. Soc. Med. 58:967 (Nov.) 1965.

Others

Anom: Plasma Concentration of Drugs and Their Efficiency, Prescribers' J. 6:48(Oct.) 1966.

Goodman L. S. and Gilman A. : The Pharmacological Basis of Therapeutics, MacMillan Co., New York, 1965, p. 15.

Milne M. D. : Clinical Effects of Interaction Between Drugs. Review of Points at Which Drugs Can Interact, Proc. Roy. Soc. Med. 58:943 (Nov.) 1965.