Distribution of Nuchal Translucency in Antenatal Screening for Down's Syndrome

(Bestwick JP, Huttly WJ, Wald NJ. J Med Screen 2010;17:8-12)

There was a formatting error in Table 2 of this paper. The two sets of truncation limits were incorrectly placed under the columns headed ‘Down's syndrome pregnancies’ and ‘Unaffected pregnancies’ in the section headed ‘Estimates from present study’. The first set should be centred under ‘Estimates from present study’ and the second under ‘Estimates from SURUSS’. The truncation limits apply to both Down's syndrome and unaffected pregnancies. The correct Table 2 is reproduced below. The authors are grateful to Glenn Palomaki for bringing this error to their attention.

Table 2

Median, standard deviation and truncation limits of NT MoM values in Down's syndrome and unaffected pregnancies: estimates from the present study and estimates from SURUSS^1,4,5

	Estimates from present study		Estimates from SURUSS
	Down's syndrome pregnancies	Unaffected pregnancies	Down's syndrome pregnancies	Unaffected pregnancies
Median NT MoM (regressed)
10 completed weeks	2.86	1	2.42	1
11 completed weeks	2.29	1	2.18	1
12 completed weeks	1.84	1	1.96	1
13 completed weeks	1.47	1	1.77	1
Standard deviation (log10 MoM)
10 completed weeks	0.2382	0.1550 *	0.2313	0.1732 *
11 completed weeks		0.1275 †		0.1439 †
12 completed weeks		0.1105 †		0.1329 †
13 completed weeks
Truncation limits (MoM)
10 completed weeks	0.50 to 2.50		0.65 to2.50
11 completed weeks	0.70 to 2.50
12 completed weeks	0.80 to 2.50
13 completed weeks	0.85 to 2.50

NT, nuchal translucency; SURUSS, Serum, Urine and Ultrasound Screening Study; MoM, multiple of the median.

*

P = 0.024.

†

P < 0.001