There is no evidence that antiretroviral therapy (ART) alone may result in complete remission of aggressive non-Hodgkin's lymphomas even though it improves the overall prognosis. We report a case in which early diffuse large B-cell lymphoma regressed completely after ART alone, raising the possibility that this may be sufficient therapy in selected cases.
BessonC, GoubarA, GabarreJ, Changes in AIDS-related lymphoma since the era of highly active antiretroviral therapy. Blood2001;98:2339–44
2.
VaccherE, SpinaM, TalaminiR, Improvement of systemic human immunodeficiency virus related non-Hodgkin lymphoma outcome in the era of highly active antiretroviral therapy. Clinl Infect Dis2003;37:1556–64
3.
RiberaJ, OriolA, MorgadesM, Safety and efficacy of cyclophosphamide, adriamycin, vincristine, prednisolone and rituximab in patients with human immunodeficiency virus-associated diffuse large B-cell lymphoma: results of a phase II trial. Br J Haematol2008;140:411–9
4.
IshimaruF. Regression of HIV-associated mucosa-associated lymphoid tissue lymphoma during highly active anti-retroviral therapy. Clin Infect Dis2008;46:1124
5.
BoulangerE, MeigninV, BaiaM, Mucosa-associated lymphoid tissue lymphoma in patients with human immunodeficiency virus infection. Br J Haematol2007;140:464–74
6.
AmengualJ, ZhangX, IbrahimS, GardnerL. Regression of HIV-related diffuse large B-cell lymphoma in response to antiviral therapy alone. Blood2008;112:4359–60
