Primary adrenal diffuse large B-cell lymphoma in HIV is a very rare, highly aggressive extra-nodal lymphoma. There is only one previous case reported in the literature. Our patient presented with isolated bilateral adrenal masses with no lymphadenopathy or visceral involvement, which made the diagnosis challenging.
LuisaBTrevisanMMarinoF. Primary bilateral adrenal B-cell lymphoma associated with EBV and JCV infection. Inf Agents Can2009; 4: 1–1.
2.
WangJSunNCRensloR. Clinically silent primary adrenal lymphoma: a case report and review of the literature. Am J Hematol1998; 58: 130–136.
3.
OzimekADieboldJLinkeR. Bilateral primary adrenal non-Hodgkin’s lymphoma and primary adrenocortical carcinoma- review of the literature. Preoperative differentiation of adrenal tumors. Endocr J2008; 55: 625–638.
4.
SwiecickaASiddaramaiahNBukowczanJ. A case of HIV presenting as primary adrenal lymphoma. Endocr Abstr2012; 29: 108–108.
5.
BowerMPalfreemanAAlfa-WaliM. British HIV association guidelines for HIV-associated malignancies 2014. HIV Med2014; 15: 1–92.
6.
NakazawaSUemuraMUjikeT. Primary adrenal lymphoma: three case reports and review of Japanese cases. Int Canc Conf J2014; 2192: 3183–3183.
7.
MozosAYeHChuangWY. Most primary adrenal lymphomas are diffuse large B-cell lymphomas with non-germinal center B-cell phenotype, BCL6 gene rearrangement and poor prognosis. Mod Pathol2009; 22: 1210–1217.
8.
EzerAParlakgumusAKocerNE. Primary adrenal non-Hodgkin’s lymphoma: report of two cases. Turk J Gastroenterol2011; 22: 643–647.
MantziosGTsirigotisPVeliousF. Primary adrenal lymphoma presenting as Addison’s disease: case report and review of literature. Ann Hematol2004; 83: 460–463.
12.
KimKMYoonDHLeeSG. A case of primary large B-cell lymphoma achieving remission with rituximab- CHOP chemotherapy. J Korean Med Sci2009; 24: 525–528.
13.
CoiffierBLepageEBriereJ. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large –B-cell lymphoma. N Engl J Med2002; 346: 235–242.
