Imaging the perfusion of contrast media in breast tumors may allow improved diagnosing and treating breast cancer.
Purpose
To compare the perfusion curve f (t) characteristics of contrast-enhanced ultrasonography in benign and malignant breast tumors.
Material and Methods
Patients with breast tumors (n = 87) were evaluated with contrast-enhanced ultrasonography and the perfusion curve f (t) parameters were calculated using Sonoliver® software to compare analysis (tumor) and reference (normal) tissue areas. Differences between breast and breast tumors were assessed.
Results
Compared to benign tumors, malignant tumors had faster enhancement time and a shorter mean transit time (all P values < 0.05). The intensity of the signal was also greater for malignant compared with benign tumors.
Conclusion
Perfusion curve f (t) parameter measurements can distinguish differences in vascular flow between malignant and benign breast tumors and may provide a new quantitative indicator of breast tumor.
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