Abstract
Interstitial Cystitis (IC) is of unknown aetiology, but recently has been associated with Sjogren's syndrome. This association is much stronger than was originally recognised. In these patients the question has always been whether the bladder symptoms were a manifestation of IC or an autoimmune process. The beneficial response seen in some patients to steroids tends to support the latter. We report a case of severe IC associated with Sjogren's syndrome in whom bladder symptoms responded to a course of steroids where other conventional management did not help. We believe that a high index of suspicion for the association of these two diseases would help treat some of the refractory cases of IC with a trial of corticosteroids.
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